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Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

Leishmaniasis is a neglected disease that is caused by different species of the protozoan parasite Leishmania, and it currently affects 12 million people worldwide. The antileishmanial therapeutic arsenal remains very limited in number and efficacy, and there is no vaccine for this parasitic disease...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Prakash, Ohm, Führing, Jana, Post, John, Shepherd, Sharon M., Eadsforth, Thomas C., Gray, David, Fedorov, Roman, Routier, Françoise H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429087/
https://ncbi.nlm.nih.gov/pubmed/30871023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050996
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