TLR7 Controls VSV Replication in CD169(+) SCS Macrophages and Associated Viral Neuroinvasion

Vesicular stomatitis virus (VSV) is an insect-transmitted rhabdovirus that is neurovirulent in mice. Upon peripheral VSV infection, CD169(+) subcapsular sinus (SCS) macrophages capture VSV in the lymph, support viral replication, and prevent CNS neuroinvasion. To date, the precise mechanisms control...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Solmaz, Gülhas, Puttur, Franz, Francozo, Marcela, Lindenberg, Marc, Guderian, Melanie, Swallow, Maxine, Duhan, Vikas, Khairnar, Vishal, Kalinke, Ulrich, Ludewig, Burkhard, Clausen, Björn E., Wagner, Hermann, Lang, Karl S., Sparwasser, Tim D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428728/
https://ncbi.nlm.nih.gov/pubmed/30930901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00466
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