Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples

We present the first large-scale methylome-wide association studies (MWAS) for major depressive disorder (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Psychiatry
Prif Awduron: Aberg, Karolina A., Dean, Brian, Shabalin, Andrey A., Chan, Robin F., Han, Laura K.M., Zhao, Min, van Grootheest, Gerard, Xie, Lin Y., Milaneschi, Yuri, Clark, Shaunna L., Turecki, Gustavo, Penninx, Brenda W.J.H., van den Oord, Edwin J.C.G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428621/
https://ncbi.nlm.nih.gov/pubmed/30242228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0247-6
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