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Synthesis and biophysical characterization of oligonucleotides modified with O2’-alkylated RNA monomers featuring substituted pyrene moieties†

Over the past three decades, a wide range of pyrene-functionalized oligonucleotides have been developed and explored for potential applications in material science and nucleic acid diagnostics. Our efforts have focused on their possible use as components of Invader probes, i.e., DNA duplexes with +1...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Karmakar, Saswata, Horrocks, Tyler, Gibbons, Bradley C., Guenther, Dale C., Emehiser, Raymond, Hrdlicka, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428582/
https://ncbi.nlm.nih.gov/pubmed/30575837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02764a
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