Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

Genetic predictions of height differ among human populations and these differences have been interpreted as evidence of polygenic adaptation. These differences were first detected using SNPs genome-wide significantly associated with height, and shown to grow stronger when large numbers of sub-signif...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sohail, Mashaal, Maier, Robert M, Ganna, Andrea, Bloemendal, Alex, Martin, Alicia R, Turchin, Michael C, Chiang, Charleston WK, Hirschhorn, Joel, Daly, Mark J, Patterson, Nick, Neale, Benjamin, Mathieson, Iain, Reich, David, Sunyaev, Shamil R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428571/
https://ncbi.nlm.nih.gov/pubmed/30895926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39702
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados