Reduced signal for polygenic adaptation of height in UK Biobank

Several recent papers have reported strong signals of selection on European polygenic height scores. These analyses used height effect estimates from the GIANT consortium and replication studies. Here, we describe a new analysis based on the the UK Biobank (UKB), a large, independent dataset. We fin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Berg, Jeremy J, Harpak, Arbel, Sinnott-Armstrong, Nasa, Joergensen, Anja Moltke, Mostafavi, Hakhamanesh, Field, Yair, Boyle, Evan August, Zhang, Xinjun, Racimo, Fernando, Pritchard, Jonathan K, Coop, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428572/
https://ncbi.nlm.nih.gov/pubmed/30895923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39725
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