Prevalence of BCR-ABL T315I Mutation in Malaysian Patients with Imatinib-Resistant Chronic Myeloid Leukemia

OBJECTIVE: Chronic Myeloid Leukemia (CML) is caused by a reciprocal translocation between chromosomes 9 and 22, t(9;22) (q34;q11) which encodes for the BCR-ABL fusion protein. Discovery of Imatinib Mesylate (IM) as first line therapy has brought tremendous improvement in the management of CML. Howev...

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Detalhes bibliográficos
Publicado no:Asian Pac J Cancer Prev
Main Authors: Yusoff, Yuslina Mat, Seman, Zahidah Abu, Othman, Norodiyah, Kamaluddin, Nor Rizan, Esa, Ezalia, Zulkiply, Nor Amalina, Abdullah, Julia, Zakaria, Zubaidah
Formato: Artigo
Idioma:Inglês
Publicado em: West Asia Organization for Cancer Prevention 2018
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428553/
https://ncbi.nlm.nih.gov/pubmed/30583336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2018.19.12.3317
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