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Super-Resolution Imaging of Amyloid Structures over Extended Times Using Transient Binding of Single Thioflavin T Molecules
Oligomeric amyloid structures are crucial therapeutic targets in Alzheimer’s and other amyloid diseases. However, these oligomers are too small to be resolved by standard light microscopy. We have developed a simple and versatile tool to image amyloid structures using Thioflavin T without the need f...
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| Опубликовано в: : | Chembiochem |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428420/ https://ncbi.nlm.nih.gov/pubmed/29953718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800352 |
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