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Natural Killer-derived exosomal miR-186 inhibits neuroblastoma growth and immune escape mechanisms.

In neuroblastoma, the interplay between immune cells of the tumor microenvironment and cancer cells contributes to immune escape mechanisms and drug resistance. In this study, we show that NK cell-derived exosomes carrying the tumor suppressor microRNA (miR)-186 exhibit cytotoxicity against MYCN-amp...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Neviani, Paolo, Wise, Petra M, Murtadha, Mariam, Liu, Cathy W, Wu, Chun-Hua, Jong, Ambrose Y, Seeger, Robert C, Fabbri, Muller
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428417/
https://ncbi.nlm.nih.gov/pubmed/30541743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0779
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