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Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in mice

CENP-F is a large, microtubule-binding protein that regulates multiple cellular processes including chromosome segregation and mitochondrial trafficking at cytokinesis. This multiplicity of functions is mediated through the binding of various partners, like Bub1 at the kinetochore and Miro at mitoch...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Peterka, Martin, Kornmann, Benoît
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428352/
https://ncbi.nlm.nih.gov/pubmed/30856164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008050
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