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A FLIPR Assay for Evaluating Agonists and Antagonists of GPCR Heterodimers

Calcium signaling plays a major role in the function of cells. Measurement of intracellular calcium mobilization is a robust assay that can be performed in a high-throughput manner to study the effect of compounds on potential drug targets. Pharmaceutical companies frequently use calcium signaling a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Methods Mol Biol
Prif Awduron: Harvey, Jessica H., van Rijn, Richard M., Whistler, Jennifer L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428067/
https://ncbi.nlm.nih.gov/pubmed/23494371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-345-9_4
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