Lipid-independent control of endothelial and neuronal TRPC3 channels by light

Lipid-gated TRPC channels are highly expressed in cardiovascular and neuronal tissues. Exerting precise pharmacological control over their activity in native cells is expected to serve as a basis for the development of novel therapies. Here we report on a new photopharmacological tool that enables m...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Tiapko, Oleksandra, Shrestha, Niroj, Lindinger, Sonja, Guedes de la Cruz, Gema, Graziani, Annarita, Klec, Christiane, Butorac, Carmen, Graier, Wolfgang. F., Kubista, Helmut, Freichel, Marc, Birnbaumer, Lutz, Romanin, Christoph, Glasnov, Toma, Groschner, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427946/
https://ncbi.nlm.nih.gov/pubmed/30997005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05536j
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