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Therapeutic Effect of Cabazitaxel and Blood-Brain Barrier opening in a Patient-Derived Glioblastoma Model

Treatment of glioblastoma and other diseases in the brain is especially challenging due to the blood-brain barrier, which effectively protects the brain parenchyma. In this study we show for the first time that cabazitaxel, a semi-synthetic derivative of docetaxel can cross the blood-brain barrier a...

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Detalles Bibliográficos
Publicado en:Nanotheranostics
Main Authors: Sulheim, Einar, Mørch, Yrr, Snipstad, Sofie, Borgos, Sven Even, Miletic, Hrvoje, Bjerkvig, Rolf, Davies, Catharina de Lange, Åslund, Andreas K.O.
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427936/
https://ncbi.nlm.nih.gov/pubmed/30899638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.31479
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