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Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles

BACKGROUND: Poly(alkyl cyanoacrylate) (PACA) nanoparticles have shown promise as drug carriers both to solid tumors and across the blood–brain barrier. Efficient drug delivery requires both high cellular uptake of the nanoparticles and release of the drug from the nanoparticles. Release of hydrophob...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Sulheim, Einar, Baghirov, Habib, von Haartman, Eva, Bøe, Andreas, Åslund, Andreas K. O., Mørch, Yrr, Davies, Catharina de Lange
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705582/
https://ncbi.nlm.nih.gov/pubmed/26743777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-015-0156-7
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