Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles

BACKGROUND: Poly(alkyl cyanoacrylate) (PACA) nanoparticles have shown promise as drug carriers both to solid tumors and across the blood–brain barrier. Efficient drug delivery requires both high cellular uptake of the nanoparticles and release of the drug from the nanoparticles. Release of hydrophob...

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Pubblicato in:J Nanobiotechnology
Autori principali: Sulheim, Einar, Baghirov, Habib, von Haartman, Eva, Bøe, Andreas, Åslund, Andreas K. O., Mørch, Yrr, Davies, Catharina de Lange
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705582/
https://ncbi.nlm.nih.gov/pubmed/26743777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-015-0156-7
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