Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response

Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years. Hirudin, a potent and specific thrombin inhibitor, has been report...

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Bibliographische Detailangaben
Veröffentlicht in:Ren Fail
Hauptverfasser: Deng, Fei, Zhang, Jingwei, Li, Yi, Wang, Wei, Hong, Daqing, Li, Guisen, Feng, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Laboratory Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427573/
https://ncbi.nlm.nih.gov/pubmed/30880546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2019.1583113
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