Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression

The TFIIH subunit XPB is involved in combined Xeroderma Pigmentosum and Cockayne syndrome (XP-B/CS). Our analyses reveal that XPB interacts functionally with KAT2A, a histone acetyltransferase (HAT) that belongs to the hSAGA and hATAC complexes. XPB interacts with KAT2A-containing complexes on chrom...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sandoz, Jérémy, Nagy, Zita, Catez, Philippe, Caliskan, Gizem, Geny, Sylvain, Renaud, Jean-Baptiste, Concordet, Jean-Paul, Poterszman, Arnaud, Tora, Laszlo, Egly, Jean-Marc, Le May, Nicolas, Coin, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426930/
https://ncbi.nlm.nih.gov/pubmed/30894545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09270-2
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