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Optogenetic stimulation of G(s)-signaling in the heart with high spatio-temporal precision
The standard technique for investigating adrenergic effects on heart function is perfusion with pharmaceutical agonists, which does not provide high temporal or spatial precision. Herein we demonstrate that the light sensitive G(s)-protein coupled receptor JellyOp enables optogenetic stimulation of...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426906/ https://ncbi.nlm.nih.gov/pubmed/30894542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09322-7 |
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