Implications of Individual QT/RR Profiles—Part 1: Inaccuracies and Problems of Population-Specific QT/Heart Rate Corrections

INTRODUCTION: Universal QT correction formulas are potentially problematic in corrected QT (QTc) interval comparisons at different heart rates. Instead of individual-specific corrections, population-specific corrections are occasionally used based on QT/RR data pooled from all study subjects. OBJECT...

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Vydáno v:Drug Saf
Hlavní autoři: Malik, Marek, Garnett, Christine, Hnatkova, Katerina, Vicente, Jose, Johannesen, Lars, Stockbridge, Norman
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426828/
https://ncbi.nlm.nih.gov/pubmed/30255349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-018-0736-1
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