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Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8(+) T Cell Families

After antigen stimulation cognate naïve CD8(+) T cells undergo rapid proliferation and ultimately their progeny differentiates into short-lived effectors and longer-lived memory T cells. Although the expansion of individual cells is very heterogeneous, the kinetics are reproducible at the level of t...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Pandit, Aridaman, De Boer, Rob J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426761/
https://ncbi.nlm.nih.gov/pubmed/30923522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00436
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