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Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8(+) T Cell Families

After antigen stimulation cognate naïve CD8(+) T cells undergo rapid proliferation and ultimately their progeny differentiates into short-lived effectors and longer-lived memory T cells. Although the expansion of individual cells is very heterogeneous, the kinetics are reproducible at the level of t...

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Publicat a:Front Immunol
Autors principals: Pandit, Aridaman, De Boer, Rob J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426761/
https://ncbi.nlm.nih.gov/pubmed/30923522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00436
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