載入...
Expanded CUG repeats in DMPK transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences
Myotonic dystrophy type 1 (DM1) is a complex neuromuscular disorder caused by expansion of a CTG repeat in the 3′-untranslated region (UTR) of the DMPK gene. Mutant DMPK transcripts form aberrant structures and anomalously associate with RNA-binding proteins (RBPs). As a first step toward better und...
Na minha lista:
| 發表在: | RNA |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2019
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426290/ https://ncbi.nlm.nih.gov/pubmed/30700578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.068940.118 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|