Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue

Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage. The etiology of dengue-associated thrombocytopenia is multifactorial and includes increased platelet clearance. The...

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Vydáno v:PLoS Pathog
Hlavní autoři: Riswari, Silvita Fitri, Tunjungputri, Rahajeng N., Kullaya, Vesla, Garishah, Fadel M., Utari, Gloria S. R., Farhanah, Nur, Overheul, Gijs J., Alisjahbana, Bachti, Gasem, M. Hussein, Urbanus, Rolf T., de Groot, Philip. G., Lefeber, Dirk J., van Rij, Ronald P., van der Ven, Andre, de Mast, Quirijn
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426266/
https://ncbi.nlm.nih.gov/pubmed/30849118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007500
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