Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue

Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage. The etiology of dengue-associated thrombocytopenia is multifactorial and includes increased platelet clearance. The...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Riswari, Silvita Fitri, Tunjungputri, Rahajeng N., Kullaya, Vesla, Garishah, Fadel M., Utari, Gloria S. R., Farhanah, Nur, Overheul, Gijs J., Alisjahbana, Bachti, Gasem, M. Hussein, Urbanus, Rolf T., de Groot, Philip. G., Lefeber, Dirk J., van Rij, Ronald P., van der Ven, Andre, de Mast, Quirijn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426266/
https://ncbi.nlm.nih.gov/pubmed/30849118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007500
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