Bromodomain and extra-terminal motif inhibitors: a review of preclinical and clinical advances in cancer therapy

Histone lysine acetylation is critical in regulating transcription. Dysregulation of this process results in aberrant gene expression in various diseases, including cancer. The bromodomain, present in several proteins, recognizes promotor lysine acetylation and recruits other transcription factors....

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Future Sci OA
Autors principals: Alqahtani, Ali, Choucair, Khalil, Ashraf, Mushtaq, Hammouda, Danae M, Alloghbi, Abduraham, Khan, Talal, Senzer, Neil, Nemunaitis, John
Format: Artigo
Idioma:Inglês
Publicat: Future Science Ltd 2019
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426170/
https://ncbi.nlm.nih.gov/pubmed/30906568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fsoa-2018-0115
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars