Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

While mutations affecting protein-coding regions have been examined across many cancers, structural variants at the genome-wide level are still poorly defined. Through integrative deep whole genome and transcriptome analysis of 101 castration-resistant prostate cancer metastases (109X tumor / 38X no...

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Publicado no:Cell
Main Authors: Quigley, David A., Dang, Ha X., Zhao, Shuang G., Lloyd, Paul, Aggarwal, Rahul, Alumkal, Joshi J., Foye, Adam, Kothari, Vishal, Perry, Marc, Bailey, Adina M., Playdle, Denise, Barnard, Travis J., Zhang, Li, Zhang, Jin, Youngren, Jack F., Cieslik, Marcin P., Parolia, Abhijit, Beer, Tomasz M., Thomas, George, Chi, Kim N., Gleave, Martin, Lack, Nathan A., Zoubeidi, Amina, Reiter, Robert E., Rettig, Matthew B., Witte, Owen, Ryan, Charles J., Fong, Lawrence, Kim, Won, Friedlander, Terence, Chou, Jonathan, Li, Haolong, Das, Rajdeep, Li, Hui, Moussavi-Baygi, Ruhollah, Goodazi, Hani, Gilbert, Luke A., Lara, Primo, Evans, Christopher P., Goldstein, Theodore C., Stuart, Joshua M., Tomlins, Scott A., Spratt, Daniel E., Cheetham, R. Keira, Cheng, Donavan T, Farh, Kyle, Gehring, Julian S, Hakenberg, Jrg, Liao, Arnold, Febbo, Phil, Shon, John, Sickler, Brad, Batzoglou, Serafim, Knudsen, Karen E., He, Housheng H., Huang, Jiaoti, Wyatt, Alexander W., Dehm, Scott M., Ashworth, Alan, Chinnaiyan, Arul M., Maher, Christopher A., Small, Eric J., Feng, Felix Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425931/
https://ncbi.nlm.nih.gov/pubmed/30033370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.039
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