Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

BACKGROUND: Large-scale genetic screening using CRISPR-Cas9 technology has emerged as a powerful approach to uncover and validate gene functions. The ability to control the timing of genetic perturbation during CRISPR screens will facilitate precise dissection of dynamic and complex biological proce...

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Vydáno v:BMC Genomics
Hlavní autoři: Sun, Ning, Petiwala, Sakina, Wang, Rui, Lu, Charles, Hu, Mufeng, Ghosh, Sujana, Hao, Yan, Miller, Christopher P., Chung, Namjin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425629/
https://ncbi.nlm.nih.gov/pubmed/30890156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5601-9
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