Genetic variation in the ATP binding cassette transporter ABCC10 is associated with neutropenia for docetaxel in Japanese lung cancer patients cohort

BACKGROUND: Docetaxel is a widely used cytotoxic agent for treatments of various cancers. The ATP binding cassette (ABC) transporter / multidrug resistance protein (MRP) ABCC10/MRP7, involved in transporting taxanes, has been associated with resistance to these agents. Since genetic variation in dru...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Sone, Kazuki, Oguri, Tetsuya, Uemura, Takehiro, Takeuchi, Akira, Fukuda, Satoshi, Takakuwa, Osamu, Maeno, Ken, Fukumitsu, Kensuke, Kanemitsu, Yoshihiro, Ohkubo, Hirotsugu, Takemura, Masaya, Ito, Yutaka, Niimi, Akio
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425580/
https://ncbi.nlm.nih.gov/pubmed/30890141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5438-2
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