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Functional Role of Solvent Entropy and Conformational Entropy of Metal Binding in a Dynamically Driven Allosteric System

Allostery is a regulatory phenomenon whereby ligand binding to one site influences the binding of the same or a different ligand to another site on a macromolecule. The physical origins of allosteric regulation remain under intense investigation. In general terms, ligand-induced structural changes,...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Capdevila, Daiana A., Edmonds, Katherine A., Campanello, Gregory C., Wu, Hongwei, Gonzalez-Gutierrez, Giovanni, Giedroc, David P.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425489/
https://ncbi.nlm.nih.gov/pubmed/29953213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02129
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