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Genomic correction of familial cardiomyopathy in human engineered cardiac tissues
In this study, we used three-dimensional human engineered cardiac tissue technology to directly show that phospholamban (PLN) R14del mutation impairs cardiac contractility and to demonstrate restoration of contractile properties with targeted genetic correction of this inheritable form of dilated ca...
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| Vydáno v: | Eur Heart J |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
European Society of Cardiology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6425468/ https://ncbi.nlm.nih.gov/pubmed/27450564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw307 |
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