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Genomic correction of familial cardiomyopathy in human engineered cardiac tissues
In this study, we used three-dimensional human engineered cardiac tissue technology to directly show that phospholamban (PLN) R14del mutation impairs cardiac contractility and to demonstrate restoration of contractile properties with targeted genetic correction of this inheritable form of dilated ca...
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| Publicado no: | Eur Heart J |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Society of Cardiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6425468/ https://ncbi.nlm.nih.gov/pubmed/27450564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw307 |
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