Defining human tyrosine kinase phosphorylation networks using yeast as an in vivo model substrate

Systematic assessment of tyrosine kinase-substrate relationships is fundamental to a better understanding of cellular signaling and its profound alterations in human diseases such as cancer. In human cells, complex signaling networks, feedback loops, conditional activity and intra-kinase redundancy...

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Publicado no:Cell Syst
Main Authors: Corwin, Thomas, Woodsmith, Jonathan, Apelt, Federico, Fontaine, Jean-Fred, Meierhofer, David, Helmuth, Johannes, Grossmann, Arndt, Andrade-Navarro, Miguel A., Ballif, Bryan A., Stelzl, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425277/
https://ncbi.nlm.nih.gov/pubmed/28837810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.08.001
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