MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients

INTRODUCTION: TP53 and MGMT alterations play a crucial role in glioblastoma (GB) pathogenesis. TP53 and MGMT function is affected by several pathologic mechanisms, such as point mutations or promoter methylation, which are well characterized. Expression of both genes can be regulated by other mechan...

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Detaylı Bibliyografya
Yayımlandı:Arch Med Sci
Asıl Yazarlar: Jesionek-Kupnicka, Dorota, Braun, Marcin, Trąbska-Kluch, Berenika, Czech, Joanna, Szybka, Małgorzata, Szymańska, Bożena, Kulczycka-Wojdala, Dominika, Bieńkowski, Michał, Kordek, Radzisław, Zawlik, Izabela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Termedia Publishing House 2017
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425218/
https://ncbi.nlm.nih.gov/pubmed/30899304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2017.69374
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