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Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis

Male gametes are generated through a specialised differentiation pathway involving a series of developmental transitions that are poorly characterised at the molecular level. Here, we use droplet-based single-cell RNA-Sequencing to profile spermatogenesis in adult animals and at multiple stages duri...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ernst, Christina, Eling, Nils, Martinez-Jimenez, Celia P., Marioni, John C., Odom, Duncan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424977/
https://ncbi.nlm.nih.gov/pubmed/30890697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09182-1
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