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Prospective study of the efficacy and utility of TP53 mutations in circulating tumor DNA as a non-invasive biomarker of treatment response monitoring in patients with high-grade serous ovarian carcinoma
OBJECTIVE: Somatic TP53 mutation (TP53(mut)) is a characteristic finding in high-grade serous ovarian cancer (HGSOC). The aim of this study was to assess the clinical efficacy and utility of TP53(mut) circulating tumor DNA (ctDNA) monitoring as a biomarker for managing HGSOC. METHODS: TP53(muts) wer...
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| Publicado no: | J Gynecol Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6424844/ https://ncbi.nlm.nih.gov/pubmed/30887755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2019.30.e32 |
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