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Kappa opioid signaling in the central nucleus of the amygdala promotes disinhibition and aversiveness of chronic neuropathic pain

Chronic pain is associated with neuroplastic changes in the amygdala that may promote hyper-responsiveness to mechanical and thermal stimuli (allodynia and hyperalgesia) and/or enhance emotional and affective consequences of pain. Stress promotes dynorphin-mediated signaling at the kappa opioid rece...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pain
Egile Nagusiak: Navratilova, Edita, Ji, Guangchen, Phelps, Caroline, Qu, Chaoling, Hein, Matthew, Yakhnitsa, Vadim, Neugebauer, Volker, Porreca, Frank
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424634/
https://ncbi.nlm.nih.gov/pubmed/30681985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001458
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