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Kappa opioid signaling in the central nucleus of the amygdala promotes disinhibition and aversiveness of chronic neuropathic pain

Chronic pain is associated with neuroplastic changes in the amygdala that may promote hyper-responsiveness to mechanical and thermal stimuli (allodynia and hyperalgesia) and/or enhance emotional and affective consequences of pain. Stress promotes dynorphin-mediated signaling at the kappa opioid rece...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pain
मुख्य लेखकों: Navratilova, Edita, Ji, Guangchen, Phelps, Caroline, Qu, Chaoling, Hein, Matthew, Yakhnitsa, Vadim, Neugebauer, Volker, Porreca, Frank
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424634/
https://ncbi.nlm.nih.gov/pubmed/30681985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001458
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