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Discovery of Novel N-(4-Hydroxybenzyl)valine Hemoglobin Adducts in Human Blood

Humans are exposed to a wide range of electrophilic compounds present in our diet and environment or formed endogenously as part of normal physiological processes. These electrophiles can modify nucleophilic sites of proteins and DNA to form covalent adducts. Recently, powerful untargeted adductomic...

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Vydáno v:Chem Res Toxicol
Hlavní autoři: Degner, Amanda, Carlsson, Henrik, Karlsson, Isabella, Eriksson, Johan, Pujari, Suresh S., Tretyakova, Natalia Y., Tӧrnqvist, Margareta
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424601/
https://ncbi.nlm.nih.gov/pubmed/30375232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00173
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