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A stochastic simulation of skeletal muscle calcium transients in a structurally realistic sarcomere model using MCell

Skeletal muscle contraction is initiated when an action potential triggers the release of Ca(2+) into the sarcomere in a process referred to as excitation-contraction coupling. The speed and scale of this process makes direct observation very challenging and invasive. To determine how the concentrat...

詳細記述

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書誌詳細
出版年:PLoS Comput Biol
主要な著者: Holash, Robert John, MacIntosh, Brian R.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424466/
https://ncbi.nlm.nih.gov/pubmed/30845143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006712
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