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Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity

Zika virus (ZIKV) is a mosquito-borne positive sense RNA virus. Recently, ZIKV emerged into the Western hemisphere as a human health threat, with severe disease associated with developmental and neurological complications. The structural envelope protein of ZIKV and other neurotropic flaviviruses co...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Dinnon III, Kenneth H., Gallichotte, Emily N., Fritch, Ethan J., Menachery, Vineet D., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424462/
https://ncbi.nlm.nih.gov/pubmed/30845254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007212
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