Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α

TRIM5α is an interferon inducible restriction factor which contributes to intrinsic defense against HIV infection by targeting the HIV capsid protein CA. Although human TRIM5α (huTRIM5α) does not potently inhibit HIV-1 infection, the ability of huTRIM5α to exhibit some control of HIV-1 infection is...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kömürlü, Sevnur, Bradley, Margret, Smolin, Nikolai, Imam, Sabrina, Pauszek, Raymond F., Robia, Seth L., Millar, David, Nakayama, Emi E., Shioda, Tatsuo, Campbell, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424450/
https://ncbi.nlm.nih.gov/pubmed/30889178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212888
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados