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Hyaluronic acid/poly(ethylenimine) polyelectrolyte multilayer coatings for siRNA-mediated local gene silencing

Local gene delivery systems utilizing RNA interference technology are a promising approach for therapeutic applications where site-specific release of agents is desired. Polyelectrolyte multilayers (PEMs) can be constructed using the layer-by-layer (LbL) technique and serve as a depot for bioactive...

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Pubblicato in:PLoS One
Autori principali: Koenig, Olivia, Neumann, Bernd, Schlensak, Christian, Wendel, Hans Peter, Nolte, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424445/
https://ncbi.nlm.nih.gov/pubmed/30889177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212584
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