Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing

Single-cell RNA sequencing is a powerful tool by which to characterize the transcriptional profile of low-abundance cell types, but its application to the inner ear has been hampered by the bony labyrinth, tissue sparsity, and difficulty dissociating the ultra-rare cells of the membranous cochlea. H...

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Udgivet i:Cell Rep
Main Authors: Ranum, Paul T., Goodwin, Alexander T., Yoshimura, Hidekane, Kolbe, Diana L., Walls, William D., Koh, Jin-Young, He, David Z.Z., Smith, Richard J.H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424336/
https://ncbi.nlm.nih.gov/pubmed/30865901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.02.053
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