Evaluation of (111)In-DOTA-5D3, a Surrogate SPECT Imaging Agent for Radioimmunotherapy of Prostate-Specific Membrane Antigen

5D3 is a new high-affinity murine monoclonal antibody specific for prostate-specific membrane antigen (PSMA). PSMA is a target for the imaging and therapy of prostate cancer. (111)In-labeled antibodies have been used as surrogates for (177)Lu/(90)Y-labeled therapeutics. We characterized (111)In-DOTA...

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Bibliographische Detailangaben
Veröffentlicht in:J Nucl Med
Hauptverfasser: Banerjee, Sangeeta Ray, Kumar, Vivek, Lisok, Ala, Plyku, Donika, Nováková, Zora, Brummet, Mary, Wharram, Bryan, Barinka, Cyril, Hobbs, Robert, Pomper, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Nuclear Medicine 2019
Schlagworte:
Theranostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424233/
https://ncbi.nlm.nih.gov/pubmed/30237212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.214403
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