(68)Ga-FAPI PET/CT: Biodistribution and Preliminary Dosimetry Estimate of 2 DOTA-Containing FAP-Targeting Agents in Patients with Various Cancers

Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts of several tumor entities. The recent development of quinoline-based PET tracers that act as FAP inhibitors (FAPIs) demonstrated promising results preclinically and already in a few clinical cases. Consequently, th...

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Vydáno v:J Nucl Med
Hlavní autoři: Giesel, Frederik L., Kratochwil, Clemens, Lindner, Thomas, Marschalek, Manfred M., Loktev, Anastasia, Lehnert, Wencke, Debus, Jürgen, Jäger, Dirk, Flechsig, Paul, Altmann, Annette, Mier, Walter, Haberkorn, Uwe
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Nuclear Medicine 2019
Témata:
Theranostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424229/
https://ncbi.nlm.nih.gov/pubmed/30072500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.215913
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