Development of Fibroblast Activation Protein–Targeted Radiotracers with Improved Tumor Retention

Cancer-associated fibroblasts constitute a vital subpopulation of the tumor stroma and are present in more than 90% of epithelial carcinomas. The overexpression of the serine protease fibroblast activation protein (FAP) allows a selective targeting of a variety of tumors by inhibitor-based radiophar...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Loktev, Anastasia, Lindner, Thomas, Burger, Eva-Maria, Altmann, Annette, Giesel, Frederik, Kratochwil, Clemens, Debus, Jürgen, Marmé, Frederik, Jäger, Dirk, Mier, Walter, Haberkorn, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2019
Assuntos:
Theranostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785792/
https://ncbi.nlm.nih.gov/pubmed/30850501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.224469
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