Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy

PURPOSE: Merkel cell carcinoma (MCC) is an aggressive skin cancer often caused by the Merkel cell polyomavirus. Clinical trials of programmed cell death-1 pathway inhibitors for advanced MCC (aMCC) demonstrate increased progression-free survival (PFS) compared with historical chemotherapy data. Howe...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Nghiem, Paul, Bhatia, Shailender, Lipson, Evan J., Sharfman, William H., Kudchadkar, Ragini R., Brohl, Andrew S., Friedlander, Phillip A., Daud, Adil, Kluger, Harriet M., Reddy, Sunil A., Boulmay, Brian C., Riker, Adam I., Burgess, Melissa A., Hanks, Brent A., Olencki, Thomas, Margolin, Kim, Lundgren, Lisa M., Soni, Abha, Ramchurren, Nirasha, Church, Candice, Park, Song Y., Shinohara, Michi M., Salim, Bob, Taube, Janis M., Bird, Steven R., Ibrahim, Nageatte, Fling, Steven P., Homet Moreno, Blanca, Sharon, Elad, Cheever, Martin A., Topalian, Suzanne L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424137/
https://ncbi.nlm.nih.gov/pubmed/30726175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01896
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