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Phase 1 Safety and Pharmacokinetics Study of MK-2048/Vicriviroc (MK-4176)/MK-2048A Intravaginal Rings

BACKGROUND: Vaginal rings (VR) containing antiretroviral (ARV) drugs can be utilized for prevention of human immunodeficiency virus (HIV) with potential for improved adherence compared to daily pills. Combination ARV VRs could improve efficacy. METHODS: MTN-027, a single-blind, randomized, placebo-c...

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Publicado en:Clin Infect Dis
Main Authors: Hoesley, Craig J, Chen, Beatrice A, Anderson, Peter L, Dezzutti, Charlene S, Strizki, Julie, Sprinkle, Carol, Heard, Faye, Bauermeister, Jose, Hall, Wayne, Jacobson, Cindy, Berthiaume, Jennifer, Mayo, Ashley, Gundacker, Holly, Richardson-Harman, Nicola, Piper, Jeanna
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424075/
https://ncbi.nlm.nih.gov/pubmed/30289435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy653
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