Phase 1 Pharmacokinetic Trial of 2 Intravaginal Rings Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

BACKGROUND: Vaginal rings (VRs) are a promising approach for sustained delivery of antiretroviral (ARV) medication to prevent human immunodeficiency virus (HIV) infection in women. Combination ARV VRs could increase efficacy. METHODS: MTN-028, a phase 1 trial in 19 HIV-uninfected women, evaluated 2...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Liu, Albert Y, Zhang, Jingyang, Anderson, Peter L, Wagner, Theresa, Pan, Zhenyu, Peda, Melissa, Gomez, Kailazarid, Beamer, May, Jacobson, Cindy, Strizki, Julie, Dezzutti, Charlene S, Piper, Jeanna M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424086/
https://ncbi.nlm.nih.gov/pubmed/30289444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy652
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