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Combined test versus logrank/Cox test in 50 randomised trials

BACKGROUND: The logrank test and the Cox proportional hazards model are routinely applied in the design and analysis of randomised controlled trials (RCTs) with time-to-event outcomes. Usually, sample size and power calculations assume proportional hazards (PH) of the treatment effect, i.e. the haza...

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Publicado en:Trials
Main Authors: Royston, Patrick, Choodari-Oskooei, Babak, Parmar, Mahesh K. B., Rogers, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424007/
https://ncbi.nlm.nih.gov/pubmed/30885277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3251-5
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