Inhibition of Notch1 Signaling Alleviates Endotoxin-Induced Inflammation Through Modulating Retinal Microglia Polarization

Microglial cells are resident immune cells and play an important role in various cerebral and retinal inflammatory diseases. Notch1 signaling is involved in the microglia polarization and the control of cerebral inflammatory reactions. However, its role in endotoxin-induced uveitis (EIU) remains unk...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cheng, Zhixing, Yang, Yao, Duan, Fang, Lou, Bingsheng, Zeng, Jieting, Huang, Yanqiao, Luo, Yan, Lin, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423918/
https://ncbi.nlm.nih.gov/pubmed/30930891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00389
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