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Nonhuman Primates and Humanized Mice for Studies of HIV-1 Integrase Inhibitors: A Review

Since the discovery of the first inhibitors of HIV replication, drug resistance has been a major problem in HIV therapy due in part to the high mutation rate of HIV. Therefore, the development of a predictive animal model is important to identify impending resistance mutations and to possibly inform...

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Опубликовано в: :Pathog Immun
Главные авторы: Hassounah, Said A., Mesplède, Thibault, Wainberg, Mark A.
Формат: Artigo
Язык:Inglês
Опубликовано: Pathogens and Immunity 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423640/
https://ncbi.nlm.nih.gov/pubmed/30993244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20411/pai.v1i1.104
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