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Novel compound heterozygous mutations in the SPTA1 gene, causing hereditary spherocytosis in a neonate with Coombs-negative hemolytic jaundice

Hereditary spherocytosis (HS) is a common heterogeneous type of inherited hemolytic anemia characterized by jaundice and splenomegaly. Diagnosis of HS in neonates is considered unreliable, and is generally based on positive family history, spherocytes in peripheral smears, increased osmotic fragilit...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Wang, Xiong, Liu, Aiguo, Lu, Yanjun, Hu, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423610/
https://ncbi.nlm.nih.gov/pubmed/30816434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.9947
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